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The actions of estrogen hormones on the female include maturation of the reproductive tract and mammary glands, modulation of pituitary gonadotropin secretion, expression of estrus behavior, enhanced uterine-resistance to infection, gestational support during pregnancy and modulation of uterine contractions, and cervical relaxation during labor. Estradiol cypionate (ECP) is an esterified estrogen that is more potent and has a longer half-life than the predominant naturally occurring estrogen, estradiol 17 beta. Search for Available Dosage Forms Basic InformationĮstradiol is the most active of the endogenous estrogens.